Suggestions by @robertbarnes

Sterling Hayden

as Abraham Whistler in Blade (1978)

John Travolta

as Deacon Frost in Blade (1978)

Tamara Dobson

as Dr. Karen Jenson in Blade (1978)

Richard Roundtree

as Blade in Blade (1978)

Colin Mochrie

as Creed Bratton in The Office (2015-2023)

Mark Ruffalo

as William Foster in Falling Down (2013)

Steve Carell

as William Foster in Falling Down (2013)

Eric Bana

as Eddie Brock in Venom (2008)

Sam Witwer

as Eddie Brock in Venom (2018)

Sean Gunn

as The Hitchhiker in The Texas Chain Saw Massacre (2014)

Jeff Goldblum

as Peter Graham in Hereditary (1978)

Patton Oswalt

as Whiskers in Last Action Hero (2013)

Verna Bloom

as Mrs. Kintner in Jaws (1985)

Ted Raimi

as Weasel in The Suicide Squad (2011)

Jay Baruchel

as Blackguard in The Suicide Squad (2011)

Craig T. Nelson

as Savant in The Suicide Squad (2011)

Ana de Armas

as Ratcatcher 2 in The Suicide Squad (2011)

Judah Friedlander

as Polka Dot-Man in The Suicide Squad (2011)

Jemaine Clement

as Polka-Dot Man in The Suicide Squad (2011)

John Noble

as The Thinker in The Suicide Squad (2011)