Suggestions by @randomcaster

Tiffany Valentine

as Jennifer Tilly in Best character each of these actors played

Chucky

as Brad Dourif in Best character each of these actors played

Edgin Darvis

as Chris Pine in Best character each of these actors played

Mantis (Marvel Cinematic Universe)

as Pom Klementieff in Best character each of these actors played

Superman (DCEU)

as Henry Cavill in Best character each of these actors played

Gamora (Zoe Saldana)

as Zoe Saldana in Best character each of these actors played

Billy Butcher

as Karl Urban in Best character each of these actors played

Shaun Riley

as Simon Pegg in Best character each of these actors played

Professor Charles Xavier

as Patrick Stewart in Best character each of these actors played

The Shame Wizard

as David Thewlis in Best character each of these actors played

Doctor Who

as David Tennant in Best character each of these actors played

Ash Williams

as Bruce Campbell in Best character each of these actors played

Chef (South Park)

as Isaac Hayes in Best character each of these actors played

Eric Cartman

as Trey Parker in Best character each of these actors played

Captain Klenzendorf

as Sam Rockwell in Best character each of these actors played

Johannes "Jojo" Betzler

as Roman Griffin Davis in Best character each of these actors played

Hannibal Lecter

as Anthony Hopkins in Best character each of these actors played

The Joker

as Heath Ledger in Best character each of these actors played

Rosie Betzler

as Scarlett Johansson in Best character each of these actors played

Frank Reynolds

as Danny DeVito in Best character each of these actors played