The Priest was the head of a church in London and was extremely fanatical and religious in his life. He sprawled religious and apocalyptic graffiti on his walls in the Outbreak. He was convinced the Outbreak of the Rage Virus was a sign of God's wrath and the events were foretold in Scripture
In the Outbreak, the Priest himself got Infected and killed all his congregation. He then lurked in a backroom of the church and was barricaded by survivors, turning his rooms into a prison
During the later days of the outbreak, Jim, having woken from his car crash-induced coma and having found himself abandoned in an empty hospital, was wandering round London, which was all deserted, when he decided to seek refuge in a church. The church seemed peaceful and empty, but in fact it was filled with corpses. Jim saw this to his disbelief and horror, and then when he asked, "Hello?" a few of the seemingly dead bodies stood up; they were Infected