While returning from a space voyage, Derek Grainer (Taron Egerton) and his friends get zapped by the Van Pattern Radiation Belt and gain superpowers. Cindy gains super-strength, Sheen gains super-speed, Libby gains invisibility, and Carl can produce sonic belches. Jimmy simply turns orange and seems to lack powers entirely, resulting in his friends and the townspeople mocking him. However, when Jimmy loses control of his temper due to Cindy's relentless insults, he turns into an orange Hulk-like monster and begins on a rampage in Retroville by causing havoc. His friends must figure how to reverse his hulking transformation so he can save them and himself from radiation poisoning.
