After Sam, a penniless Afro-German singer, discovers he's HIV positive, he gets utterly drunk, spends a few miserable days, but promptly falls (back) in love. Amidst a crumbling former East Berlin (its bulidings, cars, people & culture), Sam develops a "family" for the new millenium, for the new generation of post-drug cocktail AIDS victims. The fragile "family" he forms includes his on-again-off-again boyfriend Rainer, and his best friend Bastl with his latest fling, Mike. Like the old, schmaltzy East German songs which Sam is recording, the sweet innocence of the characters struggle to prevail, the misfortunes of the characters nothwithstanding.
Based on Michel Houellebecq's controversial novel, Atomised (aka The Elementary Particles) focuses on Michael and Bruno, two very different half-brothers and their disturbed sexuality. After a chaotic childhood with a hippie mother only caring for her affairs, Michael, a molecular biologist, is more interested in genes than women, while Bruno is obsessed with his sexual desires, but mostly finds his satisfaction with prostitutes. But Bruno's life changes when he gets to know the experienced Christiane. In the meantime, Michael meets Annabelle, the love of his youth, again.