Suggestions by @thecastmaker

Rachel Ticotin

as Mayor Marcia in James Gunn’s The Toxic Avenger 2 (2002)

Skeleton Men

as Bonehead in James Gunn’s The Toxic Avenger 2 (2002)

Jack Stauber

as Bonehead in James Gunn’s The Toxic Avenger 2 (2002)

An Animatronic

as Toxie and Sara’s Child in James Gunn’s The Toxic Avenger 2 (2002)

Marshall Bell

as Quato Hernandez in James Gunn’s The Toxic Avenger 2 (2002)

Andrew Bryniarski

as The Noxious Offender in James Gunn’s The Toxic Avenger 2 (2002)

Danny Elfman

as Fender in James Gunn’s The Toxic Avenger 2 (2002)

Jake Gyllenhaal

as Roy The Toxic Boy in James Gunn’s The Toxic Avenger 2 (2002)

Bill Duke

as Mr. Disaster in James Gunn’s The Toxic Avenger 2 (2002)

Katharine Isabelle

as Junkyard in James Gunn’s The Toxic Avenger 2 (2002)

Bruce Spence

as No-Zone in James Gunn’s The Toxic Avenger 2 (2002)

Tom Atkins

as Chief Krupke O’Clancy in James Gunn’s The Toxic Avenger 2 (2002)

Marcia Jean Kurtz

as Mirthes Herskell in James Gunn’s The Toxic Avenger 2 (2002)

Jessica Simpson

as Sara Maranda in James Gunn’s The Toxic Avenger 2 (2002)

Derek Mears

as Toxie in James Gunn’s The Toxic Avenger 2 (2002)

Takumi Tsutsui

as Sgt. Kabukiman in James Gunn’s The Toxic Avenger 2 (2002)

Derek Mears

as Toxie in James Gunn Presents: The Toxic Avenger (2000)

Flea

as Bowser Jr. in Super Mario World Adventures

Danny Elfman

as General Blue-Shell in Super Mario World Adventures

Oingo Boingo

as Composer in James Gunn Presents: The Toxic Avenger (2000)