Suggestions by @silmarils

David Lynch

as Director in Welcome to Night Vale

Tommy Lister Jr.

as Jules in The Isle Chronicles

Stef Sanjati

as Rogue in X-Men: Evolution

Kim Petras

as Kitty in Wolverine: The Lost Trail

Daniel Radcliffe

as Logan in Wolverine: The Lost Trail

Matt Ryan

as John Spector in Ghost

Mike Moh

as Triton Mander-Azur in The Fantastic Four

Noah Schnapp

as Lucas in Narnia (genderbend)

Beau Gadsdon

as Edna in Narnia (genderbend)

Tom Holland

as Samson in Narnia (genderbend)

Katherine Langford

as Petra in Narnia (genderbend)

Holly Taylor

as Susan Storm in The Fantastic Four

Gerard Way

as Narrator in The Black Parade

Billie Joe Armstrong

as Composer in American Idiot

George Clooney

as Nick Fury in X-Men: Evolution

Faran Tahir

as Mesmero in X-Men: Evolution

Gary Cole

as Principal Robert Kelly in X-Men: Evolution

Matt Lanter

as Duncan Matthews in X-Men: Evolution

Keanu Reeves

as Gambit in X-Men: Evolution

Liev Schreiber

as Sabretooth in X-Men: Evolution