Suggestions by @returnteamgoat

Jesse Eisenberg

as The Jackal in MCU Spider-Man college trilogy

Ashton Kutcher

as The Lizard in MCU Spider-Man college trilogy

O'Shea Jackson Jr.

as Overdrive in MCU Spider-Man college trilogy

Adam Copeland

as Grizzly in MCU Spider-Man college trilogy

Marvin Jones III

as Tombstone in MCU Spider-Man college trilogy

Angourie Rice

as Betty Brant in MCU Spider-Man college trilogy

Rainn Wilson

as Dr. Octopus in MCU Spider-Man college trilogy

Christian Bale

as Green Goblin in MCU Spider-Man college trilogy

Nika King

as Martha Robertson in MCU Spider-Man college trilogy

Miles Brown

as Miles Morales in MCU Spider-Man college trilogy

J.K. Simmons

as J. Jonah Jameson in MCU Spider-Man college trilogy

Tunde Adebimpe

as Robbie Robertson in MCU Spider-Man college trilogy

Marcus Scribner

as Randy Robertson in MCU Spider-Man college trilogy

Roselyn Sánchez

as Rio Morales in MCU Spider-Man college trilogy

Richard T. Jones

as Officer Jefferson Davis in MCU Spider-Man college trilogy

Eric Winter

as Captain George Stacy in MCU Spider-Man college trilogy

Dove Cameron

as Gwen Stacy in MCU Spider-Man college trilogy

Sydney Sweeney

as Black Cat in MCU Spider-Man college trilogy

Zendaya

as MJ in MCU Spider-Man college trilogy

Jacob Batalon

as Hob Goblin in MCU Spider-Man college trilogy