Suggestions by @redfox

Zendaya Coleman

as Miles Morales in Marvel Comics (Gender Swap)

Birgitte Hjort Sørensen

as Nathan Summers in Marvel Comics (Gender Swap)

Gina Carano

as Arthur Douglas in Marvel Comics (Gender Swap)

Melissa McBride

as Charles Xavier in Marvel Comics (Gender Swap)

Anya Taylor-Joy

as Harry Osborn in Marvel Comics (Gender Swap)

Michelle Fairley

as Norman Osborn in Marvel Comics (Gender Swap)

Helen Mirren

as Max Eisenhardt in Marvel Comics (Gender Swap)

Allison Williams

as Scott Summers in Marvel Comics (Gender Swap)

Viola Davis

as Nick Fury in Marvel Comics (Gender Swap)

Mary Elizabeth Winstead

as Matt Murdock in Marvel Comics (Gender Swap)

Sanaa Lathan

as James Rhodes in Marvel Comics (Gender Swap)

Maya Rudolph

as Justin Hammer in Marvel Comics (Gender Swap)

Rose Byrne

as Peter Quill in Marvel Comics (Gender Swap)

Kate Siegel

as Bucky Barnes in Marvel Comics (Gender Swap)

Bryan Cranston

as James Gordon in Batman

Zoe Saldaña

as Pamela Isley in Batman

Katie Cassidy

as Dinah Laurel Lance in Batman