Suggestions by @mr_funcaster

David Strathairn

as Uncle Ben in Ultimate Spider-Man Trilogy

Philip Seymour Hoffman

as Doctor Octopus in Ultimate Spider-Man Trilogy

Evangeline Lilly

as Black Cat in Ultimate Spider-Man Trilogy

Jessica Alba

as Kitty Pryde in Ultimate Spider-Man Trilogy

Wesley Snipes

as Nick Fury in Ultimate Spider-Man Trilogy

Julia Stiles

as Gwen Stacy in Ultimate Spider-Man Trilogy

Dwayne Johnson

as R.H.I.N.O. in Ultimate Spider-Man Trilogy

Meryl Streep

as Aunt May in Ultimate Spider-Man Trilogy

Hayden Christensen

as Venom in Ultimate Spider-Man Trilogy

Heath Ledger

as Electro in Ultimate Spider-Man Trilogy

Jake Gyllenhaal

as Hobgoblin in Ultimate Spider-Man Trilogy

Bryce Dallas Howard

as Mary Jane Watson in Ultimate Spider-Man Trilogy

Joseph Gordon-Levitt

as Spider-Man in Ultimate Spider-Man Trilogy

Spencer Treat Clark

as The Flash in Alternate DCEU

Spencer Treat Clark

as Joe Goldberg in YOU

Spencer Treat Clark

as Driver in Drive

Spencer Treat Clark

as Cal Kestis in Jedi: Fallen Order

Spencer Treat Clark

as Quicksilver in Alternate MCU

Ana de Armas

as Jyn Erso in Rogue One: A Star Wars Story

Denzel Washington

as Saw Gerrera in Rogue One: A Star Wars Story