Suggestions by @m_m_f

Tim Roth

as Emil Blonsky in What If... The Villains Fought Thanos?

Score: +1

Kathryn Hahn

as Agatha Harkness in What If... The Villains Fought Thanos?

Score: +1

Michael Keaton

as Adrian Toomes in What If... The Villains Fought Thanos?

Score: +1

Daniel Brühl

as Baron Helmut Zemo in What If... The Villains Fought Thanos?

Score: +1

Harrison Ford

as Thaddeus E. "Thunderbolt" Ross in What If... The Villains Fought Thanos?

Score: +1

Jessie Mei Li

as Betsy Braddock in The Mutant Saga

Score: +1

Denzel Washington

as Charles Francis Xavier (Professor X) in The Mutant Saga

Score: -1

Caitríona Balfe

as Auriél de León in Empire of the Vampire: season 1

Score: +1

Tom Davis

as Raphael Castia in Empire of the Vampire: season 1

Score: +1

Kylie Rae Tyndall

as Valya d'Nael in Empire of the Vampire: season 1

Score: +1

Keaton Tyndall

as Sœur Talya in Empire of the Vampire: season 1

Score: +1

Maddie Evans

as Patience de León in Empire of the Vampire: season 1

Score: +1

Charlotte Hope

as Laure Voss in Empire of the Vampire: season 1

Score: +1

Barry Keoghan

as Danton Voss in Empire of the Vampire: season 1

Score: +1

Toby Regbo

as Fabién Voss in Empire of the Vampire: season 1

Score: +1

Millie Bobby Brown

as Empress Isabella Augustin in Empire of the Vampire: season 1

Score: +1

David Oakes

as Emperor Alexandre III Augustin in Empire of the Vampire: season 1

Score: +1

Laura Donnelly

as Saoirse á Dúnnsai in Empire of the Vampire: season 1

Score: +1

Joey Batey

as Bellamy Bouchette in Empire of the Vampire: season 1

Score: +1

Giancarlo Esposito

as Père Rafa of San Guillaume in Empire of the Vampire: season 1

Score: +1