Suggestions by @m15t3rm4v3r1ck
5,549 suggestions
Rachel McAdams
as Giselle in Enchanted (2007)
Ewan McGregor
as Prince Edward in Enchanted (2007)
Meg Ryan
as Meredith Grey in Grey's Anatomy (1990's)
Derek Shepherd
as Pierce Brosnan in Which characters should actors have played in the 90's?
Leonardo DiCaprio
as Mark Sloan in Grey's Anatomy (2005 - present, alternate casting)
Sean Penn
as Benjamin "Lefty" Ruggiero in Donnie Brasco (2017)
Robert Downey Jr.
as Benjamin "Lefty" Ruggiero in Donnie Brasco (2017)
Robert Pattinson
as Joseph D. Pistone in Donnie Brasco (2017)
Adam Driver
as Joseph D. Pistone in Donnie Brasco (2017)
Leonardo DiCaprio
as Joseph D. Pistone in Donnie Brasco (2007)
Benicio del Toro
as Sonny Black in Donnie Brasco (2007)
John Travolta
as Lefty Ruggiero in Donnie Brasco (2007)
Justin Chambers
as He Cancer in Zodiac Signs
Kevin McKidd
as He Leo in Zodiac Signs
Kate Walsh
as She Libra in Zodiac Signs
John Krasinski
as He Libra in Zodiac Signs
Julia Roberts
as Addison Montgomery in Grey's Anatomy (2005 - present, alternate casting)
Matt Damon
as Alex Karev in Grey's Anatomy (2005 - present, alternate casting)
Jude Law
as Owen Hunt in Grey's Anatomy (2005 - present, alternate casting)
Christian Bale
as Owen Hunt in Grey's Anatomy (2005 - present, alternate casting)