Suggestions by @jarfddorkis

John Lithgow

as Nathaniel Bard in Resident Evil 3: Nemesis (1999)

Don Cheadle

as Tyrell Patrick in Resident Evil 3: Nemesis (1999)

Viktor Bychkov

as Mikhail Victor in Resident Evil 3: Nemesis (1999)

Vladimir Mashkov

as Nicholai Ginovaef in Resident Evil 3: Nemesis (1999)

Jay Hernandez

as Carlos Oliveira in Resident Evil 3: Nemesis (1999)

Vincent D'Onofrio

as Brad Vickers in Resident Evil 3: Nemesis (1999)

Neve Campbell

as Jill Valentine in Resident Evil 3: Nemesis (1999)

Adam Scott

as Ben Bertolucci in Resident Evil 2 (1998)

Dennis Haysbert

as Lieutenant Marvin Branagh in Resident Evil 2 (1998)

John Goodman

as Chief Brian Irons in Resident Evil 2 (1998)

David Duchovny

as William Birkin in Resident Evil 2 (1998)

Jodie Foster

as Annette Birkin in Resident Evil 2 (1998)

Amber Tamblyn

as Sherry Birkin in Resident Evil 2 (1998)

Li Bingbing

as Ada Wong in Resident Evil 2 (1998)

Keri Russell

as Claire Redfield in Resident Evil 2 (1998)

Josh Hartnett

as Leon S. Kennedy in Resident Evil 2 (1998)

Karl Urban

as Chris Redfield in Resident Evil (1996)

Victor Rivers

as Enrico Marini in Resident Evil (1996)

Eric Dane

as Richard Aiken in Resident Evil (1996)

Vincent D'Onofrio

as Brad Vickers in Resident Evil (1996)