Suggestions by @humanbeing

Andre Braugher

as Jefferson Davis in Spiderverse

Score: +1

Milly Alcock

as Gwen Stacy in Spiderverse

Score: +1

Amelia Flanagan

as Lavinia Temple in Murder Most Unladylike

Score: -2

Julie Walters

as Mel in Ink

Score: +1

Lupita Nyong'o

as Marcia Overstrand in Septimus Heap

Score: 0

Rupert Grint

as Rupert Gringe in Septimus Heap

Score: +3

Dafne Keen

as Jenna Heap in Septimus Heap

Score: +1

Freya Parks

as Leora Flint in Ink

Score: +1

Hugh Laurie

as Willikins in Discworld

Score: +3

Hugh Laurie

as The Dean in Discworld

Score: 0

Caleb McLaughlin

as Oscar Drew in Ink

Score: +1

Regé-Jean Page

as Mayor Longsight in Ink

Score: +1

Sophia Anne Caruso

as Leora Flint in Ink

Score: +1

Zendaya

as Verity Khol in Ink

Score: +1

Emma Thompson

as Lady Sybil Ramkin in Discworld

Score: -5

Cate Blanchett

as Lady Margolotta in Discworld

Score: +4

Julie Walters

as Nanny Ogg in Discworld

Score: +3

Temuera Morrison

as Samuel Vimes in Discworld

Score: -2

Temuera Morrison

as Sam Vimes in MyCast Movie

Score: +1