Suggestions by @fehermustang

Josh Hutcherson

as Fluttershy in My Little Pony (Genderswap)

Awkwafina

as Rainbow Dash in My Little Pony: Equestria Girls (Live-Action)

Skai Jackson

as Scootaloo in My Little Pony

Scarlett Johansson

as Princess Luna in My Little Pony

Lizzy Greene

as Sweetie Belle in My Little Pony

Millie Bobby Brown

as Applebloom in My Little Pony

Katherine Langford

as Starlight Glimmer in My Little Pony

Miley Cyrus

as Sunset Shimmer in My Little Pony

Margot Robbie

as Applejack in My Little Pony

Awkwafina

as Rainbow Dash in My Little Pony

Lana Condor

as Rainbow Dash in My Little Pony

Madison Pettis

as Pinkie Pie in My Little Pony

Tyler Posey

as Shining Armor in My Little Pony

Dove Cameron

as Rarity in My Little Pony

Ana de Armas

as Twilight Sparkle in My Little Pony

Drew Barrymore

as Princess Celestia in My Little Pony

Hunter Schafer

as Fluttershy in My Little Pony

Abigail Cowen

as Ginny Weasley in Harry Potter (Perfect Casting)

Taylor Lautner

as Joey Tribani in Friends

Rupert Grint

as Ross Geller in Friends