Suggestions by @elepstein

Alejandro Amenábar

as Director in The Silence of the Lambs(2011)

William H. Macy

as Dr Frederick Chilton in The Silence of the Lambs(2011)

Willem Dafoe

as Vladis Grutas in Guillermo Del Toro's Hannibal Lecter (1991-2007)

Richard Jenkins

as Multiple Miggs in Guillermo Del Toro's Hannibal Lecter (1991-2007)

John Turturro

as Inspector Pazzi in Guillermo Del Toro's Hannibal Lecter (1991-2007)

Joseph Sikora

as Mason Verger in Guillermo Del Toro's Hannibal Lecter (1991-2007)

John Carroll Lynch

as Francis Dolarhyde in Guillermo Del Toro's Hannibal Lecter (1991-2007)

Chris Thomas King

as Barney Matthews in Guillermo Del Toro's Hannibal Lecter (1991-2007)

Tommy Lee Jones

as Jack Crawford in Guillermo Del Toro's Hannibal Lecter (1991-2007)

Tim Blake Nelson

as Buffalo Bill in Guillermo Del Toro's Hannibal Lecter (1991-2007)

Joaquin Phoenix

as Ralph Mandy in Guillermo Del Toro's Hannibal Lecter (1991-2007)

William H. Macy

as Will Graham in Guillermo Del Toro's Hannibal Lecter (1991-2007)

Nick Nolte

as Frederick Chilton in Guillermo Del Toro's Hannibal Lecter (1991-2007)

John Goodman

as Freddy Lounds in Guillermo Del Toro's Hannibal Lecter (1991-2007)