Suggestions by @edritenour

D. B. Woodside

as John Shaw in Recursion

Score: +1

Neil Patrick Harris

as Miguel in The Road to El Dorado (90s)

Score: +1

Robert Downey Jr.

as Tulio in The Road to El Dorado (90s)

Score: +2

Gwendoline Christie

as Gwen in Recursion

Score: +10

Robert Maillet

as Reed in Recursion

Score: +1

Sigourney Weaver

as Dorothy Smith in Recursion

Score: +3

Vladimir Burlakov

as Sergei in Recursion

Score: +1

Bradley Cooper

as Marcus Slade in Recursion

Score: +4

Amy Adams

as Helena Smith in Recursion

Score: +2

Peyton List

as Meghan Sutton in Recursion

Score: -1

Julianna Margulies

as Julia Sutton in Recursion

Score: +3

Simon Pegg

as Barry Sutton in Recursion

Score: -13

Jude Law

as Theo in The Silent Patient

Score: -9