Suggestions by @directedbyjayst

Charlize Theron

as Sue Storm in The Chronicles of Spider-Man: Man on the Moon

Jennifer Lawrence

as Agent Natasha Romanoff in The Chronicles of Spider-Man: Sinister Six

Alicia Vikander

as Agent Jessica Drew in The Chronicles of Spider-Man: Sinister Six

Max Charles

as Billy Conners in The Chronicles of Spider-Man: Sinister Six

Madisyn Shipman

as Betty Brant in The Chronicles of Spider-Man: Sinister Six

Nicholas Hoult

as Richard Reeds in The Chronicles of Spider-Man: Sinister Six

Luis Guzman

as Gilberto Corazon in The Chronicles of Spider-Man: Sinister Six

Sadie Sink

as Mary Jane-Watson in The Chronicles of Spider-Man: Sinister Six

Jack Griffo

as Flash Thompson in The Chronicles of Spider-Man: Sinister Six

Tom Hanks

as Otto Octavious in The Chronicles of Spider-Man: Sinister Six

China Anne McClain

as Liz Allen in The Chronicles of Spider-Man: Sinister Six

Alfre Woodard

as Doris Allen in The Chronicles of Spider-Man: Sinister Six

Oquajie Williams

as Miles Morales in The Chronicles of Spider-Man: Sinister Six

Will Poulter

as Harry Osborn in The Chronicles of Spider-Man: Sinister Six

Lizzie Greene

as Gwen Stacey in The Chronicles of Spider-Man: Sinister Six

Selena Gomez

as Anya Corazon in The Chronicles of Spider-Man: Sinister Six

Ice Cube

as J. Jonah Jameson in The Chronicles of Spider-Man: Sinister Six

Charlize Theron

as Sue Storm in The Chronicles of Spider-Man: Sinister Six

George Clooney

as Nick Fury in The Chronicles of Spider-Man: Sinister Six

Ron Perlman

as Lonnie Thompson Lincoln in The Chronicles of Spider-Man: Sinister Six