Suggestions by @comodin

Anne Hathaway

as Black Cat in MCMECU (Main Classic Marvel Extended Cinematic Universe)

Score: +3

Tommy Lee Jones

as Chester Phillips in Howard Stark (early 2010's)

Score: +2

Leslie Bibb

as Christine Everhart in Iron Man 2: Armour Wars (2010)

Score: +1

Lena Headey

as Sarah Connor in The Terminator Duology (2014-2021)

Score: +1

Rosamund Pike

as Dreykov in MCU Villains (Gender Swap)

Score: +1

Demi Moore

as Malekith in MCU Villains (Gender Swap)

Score: +2

Domhnall Gleeson

as Dick Jones/Phantom Reporter in Howard Stark (early 2010's)

Score: +1

Emily Blunt

as Baroness Zemo in MCU Villains (Gender Swap)

Score: +2

Helena Bonham Carter

as real Doom in MCU Villains (Gender Swap)

Score: +1

Famke Janssen

as Jean Grey in X-Men 5: Apocalypse (2014)

Score: +1

Joaquim de Almeida

as Admiral Perkins in Doctor Erskine (early 2010's)

Score: +1

Grace Jones

as Ororo Munroe in Deadpool 2 (1978)

Score: +2

Ralph Fiennes

as President Snow in Finnicks story

Score: +1

Mike Colter

as Luke Cage in Luke Cage and Iron Fist Season 1 (2014)

Score: +1

Gabriel Luna

as Robbie Reyes in Luke Cage and Iron Fist Season 1 (2014)

Score: +1

Charlie Hunnam

as Johnny Blaze in Luke Cage and Iron Fist Season 1 (2014)

Score: +1

Zachary Levi

as Fandral in Thor: The Dark World (2013)

Score: +1