Suggestions by @aloloco

Velma Dinkley (Raja Gosnell films)

as James Gunn in Fictional Characters Sorted By Creator

Scrappy-Doo (Raja Gosnell films)

as James Gunn in Fictional Characters Sorted By Creator

Norville "Shaggy" Rogers (Raja Gosnell films)

as James Gunn in Fictional Characters Sorted By Creator

Tower Heist

as Taraji P. Henson, Michael Peña, and Alan Tudyk in Characters actors have played or will play

Family Guy (TV Show)

as James Marsden, Tom Ellis and Keke Palmer in Characters actors have played or will play

Brennan Huff and Dale Doback

as Will Ferrell and John C. Reilly in Characters actors have played or will play

Anchorman 2

as Will Ferrell and John C. Reilly in Characters actors have played or will play

Saturday Night Live

as Benedict Cumberbatch and Jack Black in Characters actors have played or will play

Saturday Night Live

as Pierce Brosnan and Dan Aykroyd in Characters actors have played or will play

Corey Large

as Corey Large in Characters actors have played or will play

Canada

as Hayden Christensen and Seth Rogen in Characters actors have played or will play

Wolves

as Keegan-Michael Key and Jordan Peele in Characters actors have played or will play

Storks

as Keegan-Michael Key and Jordan Peele in Characters actors have played or will play

Rooster Teeth

as Keegan-Michael Key and Jordan Peele in Characters actors have played or will play

Epic Rap Battles of History

as Keegan-Michael Key and Jordan Peele in Characters actors have played or will play

Get Out

as Keegan-Michael Key and Jordan Peele in Characters actors have played or will play

Mad TV

as Keegan-Michael Key and Jordan Peele in Characters actors have played or will play

Rick and Morty

as Keegan-Michael Key and Jordan Peele in Characters actors have played or will play

Red (2010)

as John Malkovich and Bruce Willis in Characters actors have played or will play

Babylon

as Mark Strong and Vin Diesel in Characters actors have played or will play