Suggestions by @625rip

Elizabeth Banks

as Betty Brant in Spider-Man 5

J.K. Simmons

as J. Jonah Jameson in Spider-Man 5

Kirsten Dunst

as Mary Jane Watson in Spider-Man 5

Alfred Molina

as Doctor Otto Octavius in Spider-Man 5

Sophia Lillis

as May 'Mayday' Parker in Spider-Man 5

Tobey Maguire

as Spider-Man in Spider-Man 5

Alan Silvestri

as Composer in Expedition

Steven Spielberg

as Director in Expedition

Emperor Sea Strider

as Emperor Sea Strider in Expedition

Beach Quills

as Beach Quills in Expedition

Groveback

as Groveback in Expedition

Skewer

as Skewer in Expedition

Daggerwrist

as Daggerwrist in Expedition

Bladderhorn

as Bladderhorn in Expedition

Unth

as Unth in Expedition

Arrowtongue

as Arrowtongue in Expedition

Eosapian

as Darwin in Expedition

Viola Davis

as Samantha Myers in Expedition

Cillian Murphy

as Ike in Expedition

Lupita Nyong'o

as Dr. Diana Sanders in Expedition