A villain who serves as the primary enemy to a specific hero.
Professor Moriarty
The Joker
Megatron
Green Goblin (Comics)
Dr Heinz Doofenshmirtz
Dr. Eggman
Magneto
The Master
Lex Luthor
Sinestro
Dr Neo Cortex
Mertle Edmonds
Bowser
Wilson Fisk
Captain Hook
Venom (Eddie Brock)
Red Skull
Doctor Octopus
Sabertooth
Wario
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