In the fallout of the multiversal crisis and Doom’s reign, millions of dormant X-Genes ignite across the globe overnight. As fear turns humanity against this sudden new species, the world responds with panic and military force, the Uncanny X-Men step into the open for the first time. They face an impossible two-front war, protect a terrified new class of mutants from government Sentinels, and stop Magneto from turning human fear into absolute annihilation.