Orphaned at the age of six, Peter Parker is an outcast and withdrawn teenaged science prodigy, who lives in Queens, New York. While attending a field trip to a scientific corporation, he is bitten by a genetically-modified spider and as a result, begins to develop spider-like superpowers. When an armed thief, whom Peter had encountered earlier and refused to stop out of spite, later murders his uncle in a robbery, a guilt-ridden Peter is later driven to use his abilities to atone for his partial responsibility in his uncle's murder, as the costumed vigilante Spider-Man. Now equipped with a responsibility to do good and help others under his Spider-Man alter-ego, Peter struggles to balance high school life and studies, his job as a web designer for the Daily Bugle, his relationship with his friend/love interest Mary-Jane Watson, his family life with his widowed aunt, and his double life as Spider-Man, as he faces off against both superhuman and criminal threats to his home of New York City and contends with the hostility of the general public and the police authorities.
