After escaping from prison and wanting revenge against Spiderman, Doctor Octopus organized a group of other arachnid villains: Electro, Kraven, Mysterio, Sandman and Vulture; thus creating the Sinister Sextet. Octavius promised an infallible plan, but what he did was arrange for the kidnapping of Betty Brant and May Parker, which caused Spider-Man to meet him. The six villains agreed to attack the hero one by one, which led to their defeat.
Tom Holland
Marisa Tomei
Angourie Rice
Tony Revolori
Timothée Chalamet
Zendaya
Jacob Batalon
J.K. Simmons
Jared Harris
Jason Momoa
Matthew McConaughey
Michael Keaton
Aaron Paul
John Cena
Jon Watts
Donald Glover
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