Fan Casting Spider-Man (Alternate Universe)

In this futuristic and non futuristic timeline, there is a universe where nothing, and I mean, nothing made sense, bad idea right? Well, this is my insane Idea, Spider-Man would be friends with Venom, his new girlfriend would be Karolina Dean, and his Ally, would be Richard Rider's Nova, in this universe, Peter Parker fights Willem Dafoe's Green Goblin and Woody Harrelson's Carnage, and Peter Parker suffers after the deaths of his Uncle Ben, Aunt May, Harry Osborn, Mary Jane and Gwen Stacy.