Fan Casting Johnny Depp as Professor James Moriarty in Sherlock Holmes in the 22nd Century

Johnny Depp is known for his roles in Pirates of the Caribbean: The Curse of the Black Pearl, Pirates of the Caribbean: Dead Man's Chest, and Fantastic Beasts and Where to Find Them. He has been suggested by fans for 12,819 roles on myCast, including Dean Casca Highbottom in The Ballad of Songbirds and Snakes. Similar actors include Keanu Reeves, Robert Downey Jr., and Willem Dafoe. Johnny Depp was suggested to play Professor James Moriarty in Sherlock Holmes in the 22nd Century by jamesthethinker. Other actors sugggested to play this role include Hugh Jackman. Sherlock Holmes in the 22nd Century has 13 roles, including Tennyson, Sherlock Holmes, and Director.