Middlesex tells the breathtaking story of Calliope Stephanides, and three generations of the Greek-American Stephanides family, who travel from a tiny village overlooking Mount Olympus in Asia Minor to Prohibition-era Detroit, witnessing its glory days as the Motor City and the race riots of 1967 before moving out to the tree-lined streets of suburban Grosse Pointe, Michigan. To understand why Calliope is not like other girls, she has to uncover a guilty family secret, and the astonishing genetic history that turns Callie into Cal.
Matthew Gray Gubler
Lachlan Watson
Maria Avgeropoulos
Christian Alexander
Mena Suvari
Zoe Kazan
Theo James
Alex Dimitriades
Tracy Spiridakos
Melina Kanakaredes
Nick Cassavetes
Tina Fey
Louis Mandylor
Amy Sedaris
John Stamos
Jennifer Aniston
Andrea Martin
Michael Constantine
Olympia Dukakis
Michael Vartan
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