Miguel O'Hara is a New York geneticist at Alchemax working to recreate the abilities of the original Spider-Man. A lab accident due to sabotage by a co-worker results in half Miguel's DNA to be re-written with a spider's genetic code. Miguel survives the process, but soon discovers he has gained spider-abilities. Miguel soon comes face-to-face with the corruption and oppression rampant among the corporations he'd turned a blind eye to while working as a corporate stooge, and is surprised to see that as the new Spider-Man, he instills a new hope in the people of New York. Miguel, as Spider-Man 2099, declares himself the enemy of the Megacorps and pledges to champion the ordinary people against their tyranny.
Diego Boneta
Guillermo del Toro
Damon Albarn
Rosie Huntington-Whiteley
Karen Fukuhara
Peter David
Iain Glen
Maria Menounos
María Conchita Alonso
Tyler Posey
Alexandra Daddario
Nathalie Emmanuel
Rachel Weisz
Britt Baron
Willa Holland
Kevin Feige
Toby Stephens
Eric Balfour
Ed Skrein
Lily Collins
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