Fan Casting Skyscraper at 10000 Feet

The movie is set in a skyscraper in America, where a huge private party is being held. Stored in a safe below the depths of the skyscraper is a suitcase containing vials of powerful venom that can kill people with just a prick. It is being protected by two British guards nicknamed Shamrock and Bullet. Frost Biscuit and Low Lightfoot are agents hired to steal the venom and destroy it so nobody gets hurt. Problem is that this venom is so powerful that all assassins want to get it for themselves. So it's a survival of the fittest.