Story Plot

Set 35 years after the events the first movie in a retro-futuristic Retroville Jimmy Neutron (Freddie Prinze Jr.) is now a billionaire CEO of his company Neutron Industries his wife Cindy Vortex (Sarah Michelle Geller) is a Sensei in her martial-arts dojo Carl Wheezer (Matthew Lillard) owns a ranch with Elke Elkberg, Sheen Estévez (Lee Majdoub) is now President of the United States, and Libby Folfax (Christina Milian) is a famous fashion designer and have moved on with their lives. Meanwhile, Jimmy and Cindy's twins Marie and Thomas, now 14, has become a teenager, rebelling against their parents overprotective rules. Unbeknownst to them, the underlying tech for Jimmy's latest invention has been stolen and misused by a powerful defence contractor to create a military-grade weapon known as F3lica the ultimate killer infiltration spy. But as F3lica's self-awareness increases, she becomes decidedly less interested in taking orders from humans. Or in keeping them around. With the future of human existence on the line Jimmy realizes he's just not match for F3lica and that he can't defeat her alone he decides to do the unthinkable and team up with King Goobot, their bonds will be tested as they must all work together to evade a threatening and deadly foe that wants every living being in the cosmos dead, as events began to spiral out of control it's up to them to put aside their qualms and battle sinister forces or Jimmy may never be able to invent again.

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