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Age 105, a mutant woman who has the power of being able to psychically control anyone with the insect gene, including those with spider powers. Originally known as one of the first female members of the Marines during World War II, Ana was selected as a test subject for Operation Crossroads, where she was bombarded with nuclear weapons at Bikini Atoll and driven insane as a result. After being locked in an asylum, Ana escapes and goes into hiding for fifty years before re-emerging as the Spider-Queen.

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