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The son of famed billionaire Norman Osborn, Harry had a hard life growing up. In fact, it was Harry who switched around some chemicals when Norman tried to create the first Goblin Serum to pay his father back for neglecting him. However, when he went to college, Harry finally found someone who would care about him far more than his father ever would: Peter Parker. While they started off rough due to Peter's life as Spider-Man, Harry soon became Peter's best friend, and they even shared an apartment. However, the strain of his father's spells as the Green Goblin eventually turned Harry to drugs, and he almost overdosed on several occasions.

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