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Fan Casting Lily-Rose Depp as Regina George in Mean Girls (2024)

user_349955 made this fan casting suggestion on June 16, 2025. What do you think? See below to cast your vote, or click here to see all fan casting suggestions for this role.

Lily-Rose Depp as Regina George in Mean Girls (2024)

Lily-Rose DeppFrance

26 years old
Lily-Rose Melody Depp (born May 27, 1999) is a French and American actress. She began her acting career with a minor role in Tusk (2014) and pursued a career as a fashion model. She starred in the ...
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Regina George in Mean Girls (2024) add character image
Fan Casting

Lily-Rose Depp

as

Regina George

in

Mean Girls (2024)

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Mean Girls (2024)

Mean Girls (2024)

What if it was made 20 years later?
by Tina Fey
The plot centers on a naïve teenage girl navigating her way through the social hierarchy of a modern American high school after years of her parents homeschooling her while conducting research in A...
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Reneé Rapp has already been officially cast for this role.

Fan casting suggestion made by:

user_349955

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Lily-Rose Depp is known for her roles in Yoga Hosers, Tusk, and The King. She has been suggested by fans for 1,720 roles on myCast, including Emily in Corpse Bride. Similar actors include Anya Taylor-Joy, Elle Fanning, and Sydney Sweeney. Lily-Rose Depp was suggested to play Regina George in Mean Girls (2024) by user_349955. Other actors sugggested to play this role include Sydney Sweeney, Millie Bobby Brown, and Dove Cameron. Mean Girls (2024) has 33 roles, including Cady Heron, Karen Smith, and Ms. Sharon Norbury.

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